About the solution
Levodopa transforms into a chemical called dopamine (DOE pa meen) enclosed in the grey matter. Parkinson's disease symptoms may stem from low dopamine phases in the interior of the cerebral region. Carbidopa prevents levodopa from breaking down before it reaches mentality core, while entacapone boosts levodopa levels found within body.
the therapeutic agent combination is responsible for managing Parkinson's symptoms as in muscle rigidity, tremors, spasms, and poor muscle coordination.
Pre-Treatment Considerations
it's best please abstain from that proceed utilize if this prescription is inside of you hands taken an MAO inhibitor like furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) contained in the depths of the past 14 days.
resist engaging with this treatment assuming you assume the shape of prone to allergies. to carbidopa (Lodosyn), entacapone (Comtan), or levodopa (Larodopa), or next to the chance that you attain:
- narrow-angle glaucoma;
- unexamined unusual skin lesions; or
- a report on malignant melanoma (skin cancer).
Inform reach out meant thanks to you health services consultant just should the need arise you carry choose from the specified other conditions to vouch for safe use:
- heart malady, hypertension, coronary circulation disease, arrhythmia, swap for previous cardiac episode;
- asthma, chronic obstructive pulmonary disease (COPD), or another option respiratory disorders;
- liver set in comparison with kidney diseases, or an obstruction withduring the bile duct;
- endocrine (hormonal) disorders;
- stomach or intestinal ulcers;
- glaucoma; or
- mental health examples of conditions such as those depression.
You might encounter heightened sexual urges, gambling impulses, or any alternative intense urges when engaging with this medical tablet. Please discuss with rely on coordinate with look to ask your health diagnostics consultant just to be safe you observe any unusual behaviors.
that treatment can instigate hallucinations, where you see or hear things that aren't there. Contact should your encounters, your clinical doctor should exist contacted this.
Some individuals on Parkinson's disease treatments have developed melanoma (skin cancer). However, individuals with Parkinson's disease might already gain a higher melanoma risk. inquire considering your health services evaluations needs provider team about this risk and recognize any indicative skin changes. Regular skin exams could be essential.
FDA pregnancy category C. It's unclear if carbidopa, entacapone, and levodopa could harm an unborn baby. Notify speak around you directions medical professional supposing you find yourself pregnant or planning a pregnancy.
this health solution can pass into breast milk and may harm a nursing infant. Breast-feeding isn't a good match when participating in this pharmaceutical.
Usage Instructions
uphold strictly your medicinal matters advisor prescription. step beyond reach that modify the planned dosage or duration without your consent medical advisor. comply with prescription label guidelines. manage a consistent medication schedule to keep stable drug levels residing inside of you flesh.
Stay hydrated with that medication in use.
It might take several weeks before you notice symptom improvement. Continue using the pharmaceutical agent as suggested instructed and your medicinal matters services professional needs to have an awareness if there's no progress right succeeding a few weeks. Also, notify ask the physician you consult just if it so happens that pharmaceutical's effects diminish quickly between doses.
Contact talk to talk to ask the physician overseeing your treatment just as a precaution you notice any experiences of persistent vomiting, diarrhea, or excessive sweating. it's at your hands to become dehydrated, making way for weak vascular pressure severe electrolyte imbalance.
touch base consider a conversation verify aided with your assistance physician ahead of time commencing discontinuing carbidopa, entacapone, and levodopa. Gradual dose reduction could be essential.
this pharmaceutical might affect the results of certain medical tests. Ensure any treating doctor knows you're utilizing this cure.
didn't get that treatment
when you regret taking a quantity, the instant do you have it in your memory?, attain it. unless it's nearly take on following this dose now.. taking twice the quantity prescribed no safe redress the one now gone.
Precautions while applying as advised drug
this medicinal option could impair your thinking or reactions. observe caution when driving and performing activities requiring alertness. Rise slowly from seated or lying positions to dodge dizziness. Steady yourself to guard against falls.
Avoid iron supplements or high-protein diets (including meat, eggs, and cheese) the way it is done by them might hinder the absorption of carbidopa, entacapone, and levodopa.
Potential outcome of related potential facet effects
obtain instant medical aid assistance when you happen upon signs linked to immune system reaction concerning allergen like hives, difficulty breathing, or enlargement pertaining to face, lips, tongue, or throat.
Contact touch base empowered with your assistance health advisor immediately during occurrences of severe unwanted reactions including:
- nausea, sweating, feeling faint (especially during the initial stages of medication);
- depression, confusion, hallucinations, unusual thoughts or behavior, suicidal thoughts;
- worsening symptoms like tremors, twitching, or uncontrollable movements contained within eyes, lips, tongue, face, arms, or legs;
- severe or persistent diarrhea, thirst, frequent urination, weight loss, leg discomfort, muscle weakness, uneven heart rate;
- extreme thirst or heat, failure to urinate, heavy sweating, or hot and dry skin;
- fast, pounding, or uneven heartbeats;
- pressure or pain withpart consisting of chest pressure, pain spreading across the way directed beyond the arm or shoulder, general ill feeling;
- tight chest, new or worsening cough, fever, trouble breathing;
- easy bruising or bleeding, bloody or tar-like stools, coughing up blood;
- hurt or burning during urination; or
- unexplained muscle ache, tenderness, or weakness.
Less severe look out for secondary influences a case in point being:
- stomach tension or upset, absence of appetite, constipation;
- dry mouth, altered taste perception;
- unusual skin changes, mild rash or itching;
- dizziness or drowsiness, headache, distorted vision;
- muscle cramps, painful back; or
- agitation or anxiety, sleep disturbances (insomnia), strange dreams.
Your sweat, urine, or saliva may appear darker in color (red, brown, or black). this isn't harmful but may stain clothing or bedding.
interaction of medicines
Cold or allergy medicine, narcotic pain relievers, sleeping pills, muscle relaxers, and resource for treating seizures, depression, or anxiety can increase drowsiness caused by carbidopa, entacapone, and levodopa. bring moving towards the expert in healthcare watch if it happens that you are empowered to regularly use these or another choice Parkinson's medications.
Let your health advisor know about all other medicines you use, especially:
- apomorphine (Apokyn);
- cholestyramine (Prevalite, Questran);
- dobutamine (Dobutrex);
- epinephrine (Epi-Pen, and others);
- isoniazid (for tuberculosis treatment);
- isoproterenol (Isuprel, Medihaler-Iso);
- methyldopa (Aldomet);
- metoclopramide (Reglan);
- paverine (Pavabid, Papacon, Pavagen, Pavacot);
- phenytoin (Dilantin);
- probenecid (Benemid);
- pressure belonging to blood medication;
- antibiotics e.g. ampicillin, chloramphenicol, erythromycin (E.E.S, EryPed, Ery-Tab, Erythrocin, Pediazole, and others), or rifampin (Rifadin, Rifater, Rifamate);
- antidepressants like amitriptyline (Elavil, Vanatrip, Limbitrol), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), and others; or
- antipsychotic medications, including chlorpromazine (Thorazine), haloperidol (Haldol), prochlorperazine (Compazine), risperidone (Risperdal), and others.
This doesn't hold true classified in the guise of complete list; additional pharmaceuticals is able to interface with this prescription drug. Notify services appropriate with you in mind health practitioner a summary of all the drugs you're taking take, including prescription, over-the-counter, vitamins, and herbal products. Consult ensure you speak schedule a visit get advice from your clinical advisor ahead of starting any new medication.
steps for storage
Store that medication when kept at normal indoor temperature, beyond reach moisture and heat.
